Tackling Antibiotic Resistance

We facilitate the application of antibacterial phage technology
in the developing world

Did You Know?

By 2050 an estimated 10 million people will die each year from antibiotic resistant infections.
Approximately 90% of those deaths will be in developing countries in Africa and Asia.
Our goal is to decrease those numbers by bringing phage technology to developing world scientists.
 

Photo courtesy Dr. Martha Clokie

What Are Phages?

  • Bacteriophages (phages) are bacteria-killing viruses in the environment, our food, and our bodies

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  • Before the discovery of antibiotics, phages were used as antibacterial products in the US, Europe & Asia

 

  • Phages have been used for >100 years in the former Soviet Union, including as over-the-counter drugs

  • Notably, phages can kill antibiotic-resistant bacteria

San Diego State video:

https://www.youtube.com/watch?v=kZKYnPLdKjg

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Photo courtesy Dr. Martha Clokie

Photo courtesy Dr. Tobi Nagel

How Can Phages Be Used?

  • The FDA and USDA have approved phage products in the US for food decontamination

  • Phages targeting bacterial pests have been developed to protect crops and livestock

  • Decades ago phages were used in India to decontaminate water during cholera outbreaks

  • Numerous phage clinical trials are ongoing in the US, France, Switzerland, Belgium, the UK, and Australia

  • Several recent cases have highlighted how phages can save people with antibiotic-resistant infections

           Man recovered after 8 months in coma

https://www.youtube.com/watch?v=XTSJ7pxIhMY&t=3s

           Phages made bacteria sensitive to antibiotics again

           100,000's of patients treated in former Soviet Union​

           https://www.youtube.com/watch?v=qTqJITdpMko

Food decontamination:

https://www.youtube.com/watch?v=ZLnfjvZ4sRc

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